Ketamine is 'magic drug' for depression

A single dose of the drug Ketamine acts like "magic" lifting people out of depression in hours and lasting more than a week, scientists claim. The drug has traditionally been used as an anaesthetic for animals and, in some cases, humans – but has also established itself as a nightclub favourite in recent years, where it is nicknamed Special K. But studies have found it can treat depression within hours, even when years of alternative treatments have failed. And the effects of just one dose can last up to 10 days. Most antidepressant drugs currently available on prescription need several months or even years to take effect and must be taken everyday. However, scientists discovered that rats given ketamine stopped displaying symptoms of depressive behaviour within hours of their first fix. The drug was even shown to restore brain-connections damaged by stress. A similar study conducted at the Connecticut Mental Health Centre also found 70 per cent of depressed patients who failed to respond to years of treatment on traditional antidepressants improved within hours of receiving a dose of ketamine.