The 2007 Nobel winners, Mario R. Capecchi, 70, of the University of Utah; Oliver Smithies, 82, of the University of North Carolina; and Sir Martin J. Evans, 66, of Cardiff University in Wales - worked independently, but their research overlapped greatly. Many other geneticists contributed to the state of the art, but the discoveries of Capecchi, Smithies, and Evans are considered watershed. 
O que fizeram os laureados em 2007, para o progresso da Medicina:
- Targeted genes responsible for specific diseases and disorders. 
- Re-combined diseased genes with normal genes to treat or eliminate specific disease. 
- Established that healthy embryonic stem cells (ES) are the only genes that can positively affect the inheritance factor in disease.